September 5, 2025BioMedInformaticsOpen Access

Real-Time Applications of Biophysiological Markers in Virtual-Reality Exposure Therapy: A Systematic Review

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Discussion

Systematic review reveals adaptive VRET with biosensing improves treatment personalization in anxiety disorders.

Adaptive virtual-reality exposure therapy shows promising personalization benefits for mental health care.
Fifteen studies analyzed, with ten employing biofeedback to tailor interventions based on physiological measures.
Systematic review identified methodological variability and small sample sizes that limit broader conclusions.
Future research should focus on more diverse clinical populations and rigorous experimental designs.

Fradette et al. (2025) studied this question.

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