September 5, 2025JAMA Network OpenOpen Access

Adverse Childhood Experiences and Health at Age 50 Years in the National Child Development Study

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Cohort study quantifies health outcomes associated with adverse childhood experiences, suggesting targeted interventions for mental health.

Adverse childhood experiences increase the risk of poor mental health and severe pain by as much as 6.50%.
The study analyzed data from 16,321 participants at age 50, revealing significant risk differences associated with ACEs.
Findings from this cohort study highlight the need for targeted interventions to address health outcomes linked to ACEs.
Specific types of ACEs like abuse and neglect show the most significant associations with adverse health outcomes.

Timmins et al. (2025) studied this question.

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Cohort study quantifies health outcomes associated with adverse childhood experiences, suggesting targeted interventions for mental health.