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September 5, 2025PLOS mental health.Open Access

UK Medical Cannabis Registry: A clinical outcomes analysis for insomnia

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Authors

AAAtul AggarwalSESimon ErridgeICIsaac Cowley

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Overview

Case series reveals significant improvements in sleep quality and anxiety in insomnia patients, suggesting cannabis efficacy.

Key Points

  • Participants showed significant improvements in sleep quality measured by the SQS over 18 months.
  • The single-item sleep quality scale improved from 2.66 to 3.81 (p < 0.001), indicating treatment effectiveness.
  • Improvements in patient-reported outcomes, including GAD-7 scores, were noted consistently at multiple follow-ups.
  • While adverse events were reported, none were disabling or life-threatening, highlighting safety for cannabis treatment.

Cite This Study

Aggarwal et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d64778d33https://doi.org/10.1371/journal.pmen.0000390
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