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September 5, 2025Frontiers in MedicineOpen Access

Comparing the longer regimen and the shorter regimen for multidrug-resistant pulmonary tuberculosis patients treated under the programmatic management of drug-resistant tuberculosis

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Authors

AKAshwin KarnanUJUlhas JadhavBGBabaji Ghewade

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Overview

Observational study finds comparable efficacy between shorter and longer regimens in MDR-TB patients, suggesting improved adherence with shorter regimens.

Key Points

  • Shorter regimens for MDR-TB led to an 88% cure rate, whereas longer regimens showed an 84% cure rate.
  • Both treatment regimens displayed similar treatment success rates, with treatment failures at 12% in both groups.
  • Assessment of treatment regimens aimed to balance efficacy, duration, and adherence among MDR-TB patients.
  • Prospective analysis involved 50 patients at a tertiary care hospital, indicating the importance of regimen length in treatment.

Cite This Study

Karnan et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d64778b2fhttps://doi.org/10.3389/fmed.2025.1645820
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