September 5, 2025Microbiology SpectrumOpen Access

Identification of an antifungal lipopeptide from Bacillus amyloliquefaciens HAU3 inhibiting the growth of Fusarium graminearum using preparative chromatography and 2D-NMR

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Isolation of Bacillus amyloliquefaciens shows antifungal activity against Fusarium graminearum, indicating potential for mycotoxin mitigation.

An antifungal lipopeptide identified from Bacillus amyloliquefaciens HAU3 effectively inhibits the growth of Fusarium graminearum.
The supernatant with 20% concentration achieved an impressive antifungal rate of 98.46% against the target fungus.
Scanning electron microscopy revealed that the strain disrupts fungal mycelial membranes, leading to hyphal collapse.
Genomic analysis revealed 13 gene clusters associated with the biosynthesis of secondary metabolites like fengycin.

Liu et al. (2025) studied this question.

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Isolation of Bacillus amyloliquefaciens shows antifungal activity against Fusarium graminearum, indicating potential for mycotoxin mitigation.