September 5, 2025GenesOpen Access

Association of Obesity-Related Genetic Variants with Android Fat Patterning and Cardiometabolic Risk in Women

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SLC30A8 genetic variant was significantly linked to android fat distribution and elevated cardiometabolic risk.
Among 15 SNPs, 3 showed significant association with waist-to-hip ratio > 0.85, highlighting genetic factors in fat distribution.
Various genetic models indicated increased susceptibility to central obesity for specific SNPs, including PSRC1 and SLC30A8.
Identifying these genetic contributions helps tailor lifestyle and pharmacological interventions to mitigate risks.

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Implication

Cohort study associates specific genetic variants with increased cardiometabolic risk in obese women, implying targeted interventions may be beneficial.

Cite This Study

Sá et al. (2025) studied this question.

synapsesocial.com/papers/68c23887b210217d64778804 https://doi.org/10.3390/genes16091019

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Implication

Cohort study associates specific genetic variants with increased cardiometabolic risk in obese women, implying targeted interventions may be beneficial.

Association of Obesity-Related Genetic Variants with Android Fat Patterning and Cardiometabolic Risk in Women

Key Points

Discussion

Implication

Cite This Study

Association of Obesity-Related Genetic Variants with Android Fat Patterning and Cardiometabolic Risk in Women

Key Points

Discussion

Implication

Cite This Study

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