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September 5, 2025InfectionOpen Access

Sero-prevalence of measles and rubella immunoglobulin G serum antibody in individuals 1–30 years old in England in 2018: implications for subsequent outbreaks prediction

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Authors

KMKhitam MuhsenYCYoon Hong ChoiJWJemma Walker

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Overview

Assessment of sero-prevalence of measles and rubella antibodies in youths, indicating outbreak potential.

Key Points

  • The overall seroprevalence for measles was 9.2%, indicating a considerable portion of the population at risk for outbreaks.
  • Using manufacturer's cutoffs, the effective reproduction number (Re) for measles was estimated at 1.00, signaling epidemic potential.
  • Mixture modelling revealed lower proportions seronegative than manufacturer's cutoffs, showing age-related antibody waning effects.
  • Seroepidemiological studies can enhance monitoring of vaccination coverage and predict the risk of future measles outbreaks.

Cite This Study

Muhsen et al. (2025) studied this question.

synapsesocial.com/papers/68c23887b210217d6477832fhttps://doi.org/10.1007/s15010-025-02630-9
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Also Consider

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  1. 1Impact of vaccination strategy adjustments on antibody levels against measles, rubella, mumps, and varicella in China: a single-center serological survey.2025
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  3. 3Assessment of immunity to the measles virus through the detection of IgG antibodies2025
  4. 4Pre- vaccination seroprevalence of rubella IgM among women of child bearing age in southeast Nigeria: a five-year cross-sectional study2026
  5. 5Seroprevalence of measles antibodies in children with cancer: results of a 2024 UK service evaluation2025