September 5, 2025Open Access

Investigating the Influence of Astringent Compounds on Oral Lubrication and the Protective Role of Proline-Rich Proteins

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EgCG increases frictional forces, disrupting lubrication in the mouth.
MUC1 structure plays a crucial role in alleviating astringency effects caused by tannins.
Proline-rich proteins improve lubrication by limiting tannin-mucin interactions.
In vitro tests using oral epithelial models confirmed the interactions between tannins and proteins.

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This study investigates how tannins affect oral lubrication in the presence of MUC1 proteins, suggesting their protective roles.

Ammam et al. (2025) studied this question.

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