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September 5, 2025PlantsOpen Access

Supercritical CO2 Antisolvent Fractionation of Citrus aurantium Flower Extracts: Enrichment and Characterization of Bioactive Compounds

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Authors

DTDhekra TrabelsiJMJosé F. Martínez-LópezMAManef Abderrabba

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Overview

This study demonstrates green technology’s potential to selectively enrich bioactive compounds from citrus aurantium, indicating significant benefits for nutraceutical and cosmetic applications.

Key Points

  • Supercritical CO2 antisolvent fractionation significantly improved compound yields from citrus aurantium flowers, enhancing extraction efficiency.
  • The main bioactive compounds identified were naringin (33.7%), neohesperidin (21.6%), and synephrine (9.0%), indicating a valuable concentration process.
  • Utilizing response surface methodology optimized extraction conditions, emphasizing pressure effects while maintaining a constant temperature.
  • ADMET predictions showed favorable properties for the flavonoids, highlighting their potential for safe applications in pharmaceuticals and cosmetics.

Cite This Study

Trabelsi et al. (2025) studied this question.

synapsesocial.com/papers/68c2384fb210217d64776f2fhttps://doi.org/10.3390/plants14172678
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