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September 5, 2025HeartOpen Access

Diagnostic performance of exercise stress testing findings and coronary microvascular dysfunction in patients with angina with non-obstructive coronary artery disease

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Authors

TTTsung‐Ying TsaiAAAli AldujeliAHAyman Haq

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Overview

Multicenter cohort study reveals exercise stress testing identifies coronary microvascular dysfunction in patients with non-obstructive coronary artery disease.

Key Points

  • Ischaemic ECG changes during exercise stress testing showed excellent diagnostic accuracy of 86.3% for detecting coronary microvascular dysfunction.
  • Exercise-induced chest discomfort had a diagnostic accuracy of 76.1%, but added no value when combined with ischaemic ECG changes.
  • Coronary microvascular dysfunction was classified using multiple criteria, with MRR <3.0 indicating structural CMD as more common.
  • The study enrolled 117 patients with non-obstructive coronary artery disease undergoing invasive coronary angiography for diagnostic assessment.

Cite This Study

Tsai et al. (2025) studied this question.

synapsesocial.com/papers/68c2384fb210217d64776f05https://doi.org/10.1136/heartjnl-2025-325769
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