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September 5, 2025ACS Food Science & Technology

Impact of Low-Molecular-Weight (<3 kDa) Camel Milk Casein and Whey Protein Hydrolysates on Hyperglycemia and Associated Hyperlipidemia, Oxidative Stress, and Reproductive Health in Type 2 Diabetic Male Rats

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Authors

SKSunny KalyanRRRakesh Kumar RamanSMSunita Meena

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Overview

Animal study shows camel milk protein hydrolysates reduce hyperglycemia and oxidative stress in type 2 diabetes, suggesting therapeutic potential for metabolic disorders.

Key Points

  • Camel milk protein hydrolysates significantly improved hyperglycemia, reducing blood glucose by 66.03% and OGTT to 148.44 mg/dL.
  • The best results were from the <3 kDa fraction, showing DPP-IV inhibition of 80.67% and increased GLP-1 secretion at 2.68 ng/mL.
  • Animal study involved diabetic male Wistar rats receiving six weeks of oral hydrolysate administration.
  • These findings support the use of camel milk protein to enhance insulin secretion and restore reproductive health in diabetes.

Cite This Study

Kalyan et al. (2025) studied this question.

synapsesocial.com/papers/68c2384fb210217d64776e08https://doi.org/10.1021/acsfoodscitech.5c00548
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