September 5, 2025New England Journal of Medicine
RSV Prefusion F Vaccine for Prevention of Hospitalization in Older Adults
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Discussion
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Implication
Pragmatic trial demonstrates RSV vaccine significantly lowers hospitalization rates in older adults, suggesting strong efficacy.
Key Points
- Hospitalization for RSV-related respiratory tract disease decreased by 83.3% in vaccinated participants, compared to controls.
- Only 3 of 65,642 in the vaccine group were hospitalized for RSV-related illness, versus 18 in the control group.
- This randomized trial included over 131,000 participants aged 60 and older to assess the vaccine's effectiveness.
- Findings highlight the potential of the RSV vaccine in preventing hospital visits for respiratory diseases among seniors.
Cite This Study
Lassen et al. (2025) studied this question.