August 19, 2025Open Access

The elusive neural signature of emotion regulation capabilities: evidence from a large-scale consortium

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Analysis of neural activation patterns during emotion regulation tasks in 2,175 individuals, suggesting varied individual reappraisal capabilities.

Findings indicate no reliable neural associations with individual emotion regulation capabilities, challenging existing assumptions.
Only a weak correlation was observed between amygdala down-regulation and task-based affective ratings, raising questions about their relationship.
Whole-brain analyses unveiled that neural associations fell outside known emotion regulation networks, complicating interpretations of fMRI data.
Results underscore methodological challenges in fMRI research, with implications for understanding emotion regulation and its connection to personality.

Sicorello et al. (2025) studied this question.

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Analysis of neural activation patterns during emotion regulation tasks in 2,175 individuals, suggesting varied individual reappraisal capabilities.