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August 17, 2025Indus journal of bioscience research.Open Access

Prevalence of ESBL Producing and Carbapenem-resistant E. Coli in Urinary Tract Infection from Tertiary Care Hospital

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Authors

ZKZahid Ullah KhanTHTaqweem Ul HaqJAJamil Ahmad

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Overview

Cross-sectional analysis of 324 urinary samples shows high ESBL prevalence, suggesting urgent intervention for antibiotic resistance.

Key Points

  • The study found 66.6% of E. coli isolates produced extended-spectrum β-lactamases, indicating high antibiotic resistance.
  • Carbapenem-resistant E. coli was identified at a lower prevalence of 6.6% among ESBL producers; highlighting concern for treatment options.
  • Gram staining and biochemical testing confirmed E. coli as a leading cause of urinary tract infections in a sample of 324 patients.
  • The high resistance rates observed emphasize the need for better antibiotic stewardship in managing UTIs.

Cite This Study

Khan et al. (2025) studied this question.

synapsesocial.com/papers/68c2368eb210217d64774bd3https://doi.org/10.70749/ijbr.v3i7.1833
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  1. 1Antibiotic Susceptibility Profile of Carbapenem Resistant Escherichia Coli and Klebsiella Pneumoniae in Urinary Isolates from a Tertiary Care Hospital: An Observation Study2025
  2. 2Prevalence of Extended Spectrum β-lactamase and AmpC β-lactamase among Escherichia coli and Klebsiella pneumoniae in Urinary tract infections2025 · 3 citations
  3. 3Detection of Extended-Spectrum β-Lactamase Producing Escherichia coli and Klebsiella pneumoniae in Urinary Tract Infection in Selected Baghdad Hospitals2025
  4. 4Comprehensive Analysis of Urinary Tract Infections: Investigating Risk Factors, Antimicrobial Resistance Profiles, and Beta-lactamase Genotyping for Effective Management Strategies2025 · 1 citations
  5. 5Antimicrobial resistance patterns of Escherichia coli and Klebsiella pneumoniae isolated from patients with urinary tract infections: a prospective study from a tertiary care hospital in Hyderabad2025 · 1 citations