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August 17, 2025Hepatitis MonthlyOpen Access

Clinical Significance and Factors Influencing T-Lymphocyte PD-1/PD-L1, Serum Autoimmune Antibodies and Erythrocyte Distribution Width in Patients with Autoimmune Hepatitis

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Authors

CWChengcheng WangDMDewen MaoYWYanan Wei

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Overview

Retrospective analysis identifies T-lymphocyte PD-1/PD-L1 and serum antibodies as significant risk factors for autoimmune hepatitis, suggesting potential diagnostic improvements.

Key Points

  • T-lymphocyte PD-1/PD-L1 and serum autoimmune antibodies significantly elevate the risk of autoimmune hepatitis.
  • Anti-nuclear antibody positivity was found in 53.40% of patients, contrasting sharply with 5.04% in controls.
  • The study used multivariate logistic regression to identify independent risk factors affecting autoimmune hepatitis occurrence.
  • ROC analysis confirmed strong predictive value for the evaluated markers, indicating their potential for early disease detection.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c2366fb210217d647749f0https://doi.org/10.5812/hepatmon-161250
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