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August 17, 2025Archives of Biological SciencesOpen Access

Resveratrol alleviates hyperlipidemia, inflammation, and oxidative stress in poloxamer 407-induced hyperlipidemic adult Wistar rats

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Authors

MJMohammed JeelaniAIAdamu Imam Isa

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Overview

Observational analysis improves lipid profiles and reduces inflammation in hyperlipidemic Wistar rats, suggesting resveratrol's therapeutic potential.

Key Points

  • Resveratrol treatment improved lipid profiles, reducing total cholesterol and triglycerides while increasing HDL levels.
  • Atherogenic and Castelli’s risk indices were significantly lowered, enhancing cardiovascular balance in treated groups.
  • Assessment involved biochemical analysis of blood samples and cardiac tissues from Wistar rats over 21 days.
  • These results highlight resveratrol's lipid-regulating, antioxidant, and anti-inflammatory properties against induced hyperlipidemia.

Cite This Study

Jeelani et al. (2025) studied this question.

synapsesocial.com/papers/68c23652b210217d6477407bhttps://doi.org/10.2298/abs250611022j
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