August 16, 2025VirusesOpen Access

Phage Therapy: Combating Evolution of Bacterial Resistance to Phages

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This review demonstrates effective strategies to combat bacterial resistance in phage therapy, suggesting innovative approaches for treatment.

Combating bacterial resistance involves utilizing different phage strategies simultaneously, enhancing treatment efficacy.
Key approaches include phage substitution and employing phage cocktails to target multiple bacterial characteristics.
Phage therapy employs various methods, including phage engineering and sourcing from phage banks, to overcome resistance challenges.
Using phages alongside antibiotics may enhance treatment outcomes and minimize bacterial adaptation risks.

Stephen T. Abedon (2025) studied this question.

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This review demonstrates effective strategies to combat bacterial resistance in phage therapy, suggesting innovative approaches for treatment.