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August 15, 2025Current Issues in Molecular BiologyOpen Access

Flavonoids from Cercidiphyllum japonicum Exhibit Bioactive Potential Against Skin Aging and Inflammation in Human Dermal Fibroblasts

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Authors

MKMinseo KangSLSanghyun LeeDJDae Sik Jang

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Overview

Observational analysis revealed ellagic acid effectively reduces inflammation in human dermal fibroblasts, suggesting its potential as a natural anti-aging agent.

Key Points

  • Ellagic acid significantly reduced reactive oxygen species generation and increased collagen production, pointing to its protective role against skin aging.
  • In human dermal fibroblasts, ellagic acid inhibited inflammatory cytokines and demonstrated impressive antioxidant effects.
  • Analysis of flavonoids from Cercidiphyllum japonicum showed ellagic acid was the most active compound, outpacing others in efficacy.
  • Overall findings highlight ellagic acid's promise in developing natural therapies for skin aging and inflammatory conditions.

Cite This Study

Kang et al. (2025) studied this question.

synapsesocial.com/papers/68c235ccb210217d6477249ehttps://doi.org/10.3390/cimb47080631
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