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August 15, 2025Journal of Clinical MedicineOpen Access

First- and Second-Trimester Uterine Artery Doppler and Hypertensive Disorders in Twin Pregnancies

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Authors

SSStephanie SpringerTATeresa AnzböckKWKatharina Worda

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Overview

Retrospective cohort study reveals uterine artery doppler measurements can indicate preeclampsia risk in twin pregnancies, suggesting enhanced monitoring.

Key Points

  • Preeclampsia risk increases significantly with elevated mean uterine artery pulsatility index (UTPI) during early and mid-pregnancy, emphasizing its predictive value.
  • Regression analysis indicates that a mean UTPI above the cut-off might predict preeclampsia and adverse outcomes in twin pregnancies.
  • Study included 554 women with twin pregnancies, where 51 women developed preeclampsia, translating to about 9.2% of the cohort.
  • Gestational weeks 11 to 22 are critical periods for UTPI measurements to assess preeclampsia risk in twin pregnancies.

Cite This Study

Springer et al. (2025) studied this question.

synapsesocial.com/papers/68c235ccb210217d64771ee1https://doi.org/10.3390/jcm14155563
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Uterine artery Doppler at 11-14 weeks of gestation in the prediction of preeclampsia: An observational study.2025
  2. 2Comparison of Pulsatility Index and Notching of Uterine Artery Doppler on Normotensive Pregnancy and Established Pre-eclampsia2025
  3. 3Diagnostic Accuracy of First Trimester Uterine Artery Doppler Ultrasonography in Predicting Pre-Eclampsia in High Risk Patients, Taking Development of Pre-Eclampsia as Gold Standard2025
  4. 4Umbilical Artery Doppler Velocimetry Along With Uric Acid Values for the Screening of Preeclampsia in Second Trimester of Pregnancy2023
  5. 5Combined Placental Laterality and Mid-Trimester Uterine Artery Dopplers; A Promising Tool for Predicting Preeclampsia Onset in Low-Resource Settings2025