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August 14, 2025Journal of Applied Oral ScienceOpen Access

Antioxidant potential of wine polyphenols on hematological indices and apical periodontitis in male rats

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Authors

RSRomulo de Oliveira Sales-JuniorJAJ. AlvaradoBPBruno M. Pereira

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Implication

Observational analysis found dealcoholized red wine reduced periapical lesions in male rats, suggesting antioxidant benefits.

Key Points

  • Dealcoholized red wine supplementation resulted in reduced periapical lesion size and altered blood profiles.
  • The DRW and alcohol groups had smaller lymphocyte counts, while the control and DRW groups had higher weight gain percentages.
  • Thirty-two male Wistar rats with induced apical periodontitis were divided into four supplementation groups over 60 days.
  • The study reveals the antioxidant potential of wine polyphenols affecting blood cells and the redox state.

Cite This Study

Sales-Junior et al. (2025) studied this question.

synapsesocial.com/papers/68c23595b210217d64771a5dhttps://doi.org/10.1590/1678-7757-2025-0229
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