Phages connect the biological dots of antimicrobial resistance: from genesis and spread to alternative treatment modules

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Observational analysis reveals phages may propagate and mitigate antimicrobial resistance, suggesting new treatment options for infections.

Phages may help both spread and combat antimicrobial resistance, indicating their dual role in infection treatment.
Evidence suggests phages contribute to antimicrobial resistance through transduction and possibly conjugation and transformation.
Phage therapy has shown effectiveness in targeting multi-drug resistant pathogens while also disrupting biofilms.
Regulatory hurdles and phage resistance present challenges, yet integrating phages with antibiotics may enhance public health efforts.

Anastassopoulou et al. (2025) studied this question.

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Observational analysis reveals phages may propagate and mitigate antimicrobial resistance, suggesting new treatment options for infections.