Hepatic metastasis of pulmonary large cell neuroendocrine carcinoma: A case report and literature review

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Case report details hepatic metastasis from pulmonary large cell neuroendocrine carcinoma, suggesting its aggressive nature.

In this case, hepatic metastasis was detected through a lesion in a patient with pulmonary large cell neuroendocrine carcinoma.
Histopathological examination confirmed the diagnosis after hepatic segmentectomy and lobectomy surgeries.
The patient, a man in his early 60s, underwent surgery due to complications from advanced malignancy.
Clinicians should remain vigilant for signs of large cell neuroendocrine carcinoma in patients presenting with multifocal malignancies.

Wu et al. (2025) studied this question.

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