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August 11, 2025Romanian Journal of PediatricsOpen Access

Lactulose and PEG-4000 treatment in constipated cerebral palsy children: a randomized clinical trial

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Authors

ADAndy DarmaAAAlpha Fardah AthiyyahKSKhadijah Rizky Sumitro

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Overview

Observational analysis reveals significant disparities in iron metabolism between steroid-sensitive and steroid-resistant nephrotic syndrome in children, suggesting the need for tailored treatments.

Key Points

  • Steroid-resistant nephrotic syndrome patients had lower hemoglobin levels and impaired iron metabolism compared to steroid-sensitive patients, indicating a more severe condition.
  • Key findings include lower serum iron levels and increased urinary albumin-to-creatinine ratios in steroid-resistant nephrotic syndrome patients, emphasizing disease severity.
  • Observed differences between the steroid-sensitive and steroid-resistant nephrotic groups highlight the importance of personalized treatment strategies.
  • The study indicates that children with steroid-resistant nephrotic syndrome may require additional interventions to manage anemia and enhance health outcomes.

Cite This Study

Darma et al. (2025) studied this question.

synapsesocial.com/papers/68c2354db210217d6476fae6https://doi.org/10.37897/rjp.2025.2.11
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Age correlation with childhood nephrotic syndrome2025
  2. 2EPIDEMIOLOGY AND CLINICOPATHOLOGIC CHARACTERISTICS OF CHILDHOOD NEPHROTIC SYNDROME IN LIBYA SINGLE CENTER EXPERIENCE2025
  3. 3Steroid response and outcomes in childhood nephrotic syndrome: A multicenter, cross-sectional study from Jordan2025
  4. 4Evaluation of Outcomes in Early Versus Late Steroid-resistant Nephrotic Syndrome in Children: An Observational Study2023
  5. 5Nutritional support for children with cerebral palsy: experience in the use of oedematous enteral nutrition in children2025