Exploratory Studies of Effective Antimicrobial Agents for the Treatment of Bovine Mastitis

The article presents the data on microbial contamination of milk received from cows with clinical mastitis on farms in Voronezh Region, and the sensitivity of the isolated microflora to antibacterial agents has also been studied. For bacteriological examination, 111 milk samples were collected from lactating animals with clinical mastitis. 172 cultures were isolated, including Staph. aureus – 23.3%, Staph. epidermidis – 9.3%, Staph. haemolyticus – 5.8%, Strept. agalactiae – 14.5%, Strept. uberis – 11.62%, Strept. dysgalactiae – 5.82%, E. сoli – 9.30%, Ent. faecium – 6.40%, Pr. mirabillis – 3.48%, Ps. aeruginosa – 2.33%, yeast-like fungi Candida – 8.15%. The isolated microorganisms were tested for sensitivity to 17 antibacterial drugs. The highest sensitivity to the isolated cultures from the udder secretion of cows with clinical mastitis among the tested antibacterial drugs is demonstrated by ceftiofur – 93.0%, florfenicol – 92.4%, marbofloxacin – 84.2%. The lowest sensitivity to the studied microorganisms is demonstrated by lincomycin – 13.3%, benzylpenicillin – 22.8%, streptomycin – 30.3%.