August 11, 2025

Exploring the Impact of Initiating Endocrine Therapy on Metabolic Health in Early Breast Cancer: Protocol for the Prospective Follow-up EMETA-study (Preprint)

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Prospective study examines endocrine therapy effects on metabolic health in women with breast cancer, suggesting new health classifications.

Changes in metabolic health were noted following initiation of endocrine therapy, impacting both weight and metabolic parameters.
A total of 112 women with early-stage breast cancer were enrolled, with follow-up occurring at 3 months post-therapy initiation.
Assessments involved biometric and laboratory measures to evaluate metabolic health, using standard and extended definitions of metabolic syndrome.
Findings could identify patients at higher risk for cardiovascular disease and improve monitoring of metabolic health post-treatment.

Nissen et al. (2025) studied this question.

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Prospective study examines endocrine therapy effects on metabolic health in women with breast cancer, suggesting new health classifications.