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August 11, 2025The EuroBiotech JournalOpen Access

Messaging malignancy: Tumour-derived exosomes at the nexus of immune escape, vascular remodelling and metastatic competence

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Authors

DYDuygu T. YildirimAYAbdulbaki YildirimMSMichel Salzet

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Overview

Review highlights the role of tumor-derived exosomes in immune escape and angiogenesis, suggesting challenges to clinical applications.

Key Points

  • Tumor-derived exosomes play a crucial role in immune escape and metastasis, impacting treatment outcomes significantly.
  • Significant challenges in the clinical application of exosomes arise from isolation and standardization issues in their profiling.
  • High-throughput technologies have advanced exosomal cargo profiling, revealing complexities in their molecular biogenesis.
  • Understanding the interplay between exosomes and angiogenesis is essential for addressing therapy resistance and improving patient outcomes.

Cite This Study

Yildirim et al. (2025) studied this question.

synapsesocial.com/papers/68c23528b210217d6476f334https://doi.org/10.2478/ebtj-2025-0018
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Dual Role of Exosomes in the Tumor Microenvironment: From Pro‐Tumorigenic Signaling to Immune Modulation2025
  2. 2EXOSOMES, KEY FACTORS IN THE REGULATION AND DEVELOPMENT OF THE TUMOR NICHE2025
  3. 3Exosomal miRNAs: Key Regulators of the Tumor Microenvironment and Cancer Stem Cells2025
  4. 4The Emerging Role of Exosome-Derived miRNAs in Cancer and Cancer Stem Cells2025
  5. 5Multidimensional insights into exosomes in hepatocellular carcinoma: from genesis to clinical application2025