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August 11, 2025

Can family cohesion and parent-child relationship quality buffer the effects of parental adverse childhood experiences on adolescent epigenetic age acceleration?

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Authors

JZJenny Zhen‐DuanALAlexandre A. LussierAWAnna E. Wilson

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Overview

Observational analysis reveals family cohesion and parent-child relationship quality moderate epigenetic age in youth, suggesting vital intervention points.

Key Points

  • Parents' adverse childhood experiences (ACEs) are linked to accelerated biological aging in adolescents, highlighting a key developmental impact.
  • Data collected from 120 families shows that both fathers’ and mothers’ ACEs relate to epigenetic age acceleration, moderated by family factors.
  • The study employed path analysis to examine associations between parental experiences and youth epigenetic markers, indicating complex relationships.
  • Understanding these dynamics may enable targeted interventions to address intergenerational biological outcomes stemming from family ACEs.

Cite This Study

Zhen‐Duan et al. (2025) studied this question.

synapsesocial.com/papers/68c23528b210217d6476f2fbhttps://doi.org/10.31234/osf.io/25dmy_v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence and correlates of adverse childhood experiences in fathers: A systematic review and meta-analysis2025 · 8 citations
  2. 2Intergenerational Effects of Adversity on Adolescent Self-Efficacy: The Role of Parental Self-Regulation2025
  3. 3Younger Maternal Age at Childbirth and Children's Exposure to ACEs : Parental Emotional Support as a Moderator2025
  4. 4Cumulative psychosocial factors and epigenetic age acceleration in the Hispanic Community Health Study/Study of Latinos2025 · 3 citations
  5. 5Increased Pregnancy Complications Among Mothers With Adverse Childhood Experiences: Findings From a Cross‐Sectional Study2026