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August 26, 2025Clinical and Translational GastroenterologyOpen Access

Dupilumab for adult and adolescent patients with primary eosinophilic colitis

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Authors

TSTwan SiaLBLeeon BacchusAKAparna Kumar

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Overview

Retrospective analysis shows significant improvement in symptoms with dupilumab in patients with eosinophilic colitis, suggesting its potential as an effective treatment option.

Key Points

  • All four patients showed improvement in histology after treatment with dupilumab, indicating its effectiveness.
  • Three out of four patients achieved histologic remission, illustrating strong treatment potential.
  • Retrospective chart review assessed clinical response to dupilumab in patients with eosinophilic colitis.
  • Findings suggest dupilumab could be an important option for managing eosinophilic gastrointestinal disorders.

Cite This Study

Sia et al. (2025) studied this question.

synapsesocial.com/papers/68af7dfe7567bf4f94ff54d5https://doi.org/10.14309/ctg.0000000000000908
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy and Safety of Dupilumab in Eosinophilic Esophagitis: A Systematic Review and Meta-Analysis2026
  2. 2Dupilumab Administration in the Patient with Severe Eosinophilic Esophagitis Combined with T2-Associated Diseases: Case Study2025
  3. 3Real-World Experience of Dupilumab Treatment for Patients with COPD – A Single Center Prospective Study2025
  4. 4Determinants of Clinical Remission in Dupilumab-Treated Severe Eosinophilic Asthma: A Real-World Retrospective Study2025 · 1 citations
  5. 5Dupilumab efficacy in children aged 6 months to younger than 6 years with moderate-to-severe atopic dermatitis and clinical characteristics of early super-responders2026