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August 26, 2025PLoS ONEOpen Access

Evaluating the associations and predictive performance of triglyceride-glucose index and related indicators for chronic diseases in a Chinese cohort

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Authors

HLHongli LiuXMXinmei MaoXWXuechen Wang

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Overview

Retrospective observational cohort study reveals links between triglyceride-glucose index and chronic diseases, suggesting its predictive value.

Key Points

  • The triglyceride-glucose index is positively associated with diabetes, heart disease, and hypertension, signaling a potential risk factor.
  • Harrell's C-index shows that TyG-WC outperforms other indicators in predicting chronic disease risks in the elderly population.
  • Using longitudinal data from CHARLS, the study analyzed almost 13,000 participants between 2011 and 2020 to establish these associations.
  • Understanding these relationships may help in early intervention strategies for managing chronic diseases in middle-aged and elderly individuals.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68af7df87567bf4f94ff5351https://doi.org/10.1371/journal.pone.0330711
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