Prospective comparative study assesses accuracy and variability of global longitudinal strain in different echocardiographic methods, indicating caution in comparing results.
Key Points
The left ventricular global longitudinal strain was found to be highly reproducible across different acquisition methods, but variability remains a concern.
Mean GLS values showed a small difference among most 2D acquisition methods, with a notable decline in 3D measurements indicating non-interchangeability.
Intra- and inter-observer variability for 2D GLS was excellent, suggesting strong reliability in this analysis approach.
The study emphasizes the importance of standardizing methods to successfully utilize GLS as a clinical tool in detecting heart dysfunction.