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August 11, 2025American Journal of Physical Medicine & Rehabilitation

Effects of Transcranial Magnetic Stimulation on Patients of Poststroke Upper Extremity Motor Impairment: A Randomized, Controlled Trial

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Authors

XZXinwei ZhuLJLe JiaoQCQingmei Chen

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Overview

Randomized trial finds enhanced motor recovery in stroke patients using theta burst stimulation and LF-rTMS, suggesting effective rehabilitation approaches.

Key Points

  • Both cTBS and LF-rTMS significantly improved upper limb function compared to sham stimulation at follow-ups, highlighting their therapeutic potential.
  • On the Fugl-Meyer Assessment, the cTBS and LF-rTMS groups showed improved scores at both 4 and 12 weeks, suggesting lasting effects.
  • Using functional near-infrared spectroscopy, active treatments decreased activation in the contralesional motor cortex, indicating targeted neuromodulation benefits.
  • The combination of cTBS and LF-rTMS may provide innovative, non-invasive options for enhancing post-stroke rehabilitation efforts.

Cite This Study

Zhu et al. (2025) studied this question.

synapsesocial.com/papers/68af7dec7567bf4f94ff494fhttps://doi.org/10.1097/phm.0000000000002792
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of low-frequency repetitive transcranial magnetic stimulation combined with motor imagery training on upper limb motor recovery and primary motor cortex activation in stroke patients: A randomized controlled trial2025 · 1 citations
  2. 2A meta-analysis of the effects of transcranial magnetic stimulation on hand function and daily living ability after stroke2025
  3. 3Optimizing Repetitive Transcranial Magnetic Stimulation (rTMS) Protocols for Upper Limb Motor Recovery in Post-Stroke Patients: A Meta-Analysis2025
  4. 4Effects of 10-Hz rTMS over the leg motor cortex using a double-cone coil on lower limb motor recovery in subacute stroke: a randomised, double-blind, sham-controlled study2025 · 3 citations
  5. 5Effects of repetitive transcranial magnetic stimulation on electroencephalographical measures of post-stroke upper limb dysfunction: study protocol for a randomized controlled trial2025