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August 16, 2025Journal of Health Systems ResearchOpen Access

Ameliorative Effects of Cucurbita Pepo L. Seed Oil on Inflammation and Oxidative Stress Induced by High-Cholesterol Diet in Male Wistar Rats

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Authors

ZBZ.M. BonomiAIAli Siddiq Idoko

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Overview

Experimental study shows pumpkin seed oil reduces inflammation and oxidative stress in male Wistar rats on high-cholesterol diet, suggesting its potential dietary benefits.

Key Points

  • Pumpkin seed oil supplementation reduces inflammatory markers in male Wistar rats on a high-cholesterol diet.
  • After 9 weeks of treatment, significant improvements in antioxidant activities were observed alongside decreased oxidative stress levels.
  • The analysis measured serum concentrations of various inflammatory cytokines and oxidative stress markers, demonstrating the oil's protective effects.
  • These findings support the idea that including pumpkin seed oil in diets could mitigate metabolic issues related to high cholesterol.

Cite This Study

Bonomi et al. (2025) studied this question.

synapsesocial.com/papers/68af7c997567bf4f94ff4780https://doi.org/10.70382/sjhsr.v9i3.035
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