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August 26, 2025World Journal of Psychiatry

Depressive state on cardiac remodeling and left ventricular function in chronic heart failure: A retrospective study

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Authors

BGBo GaoThe University of SydneyYGYuan GaoChinese Academy of Medical Sciences & Peking Union Medical CollegeMCMingxing ChuChinese Academy of Agricultural Sciences

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Implication

Retrospective study finds depression worsens cardiac remodeling and impairs left ventricular function in CHF patients, suggesting inflammatory mechanisms.

Key Points

  • Depression significantly alters heart structure and function in chronic heart failure patients, leading to poorer health outcomes.
  • Patients with depression exhibited a reduced left ventricular ejection fraction, indicating compromised heart efficiency.
  • Retrospective analysis of 248 CHF patients showed elevated inflammatory marker levels associated with depressive symptoms.
  • Results suggest that addressing depression in CHF patients may improve cardiac health and functionality.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68af7c947567bf4f94ff442bhttps://doi.org/10.5498/wjp.v15.i9.106906
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