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August 1, 2025童綜合醫學雜誌Open Access

Mechanisms of antioxidative and anti-inflammatory treatments in chronic kidney disease and the potential benefits of hydrogen therapy: A narrative review

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Authors

YPYing‐Ru PanYHYi‐Hsien HsiehTWTsai-Kun Wu

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Overview

Narrative review highlights the role of oxidative stress and hydrogen therapy in chronic kidney disease management.

Key Points

  • Hydrogen therapy reduces all-cause mortality in patients with chronic kidney disease, easing inflammation and supporting cell protection.
  • Evidence shows hydrogen therapy positively influences oxidative stress and inflammation through modulation of redox-sensitive pathways.
  • The review discusses various antioxidant treatments, including NRF2 activators and SGLT2 inhibitors, targeting oxidative damage.
  • Chronic kidney disease progression is exacerbated by excessive reactive oxygen species and impaired antioxidant systems.

Cite This Study

Pan et al. (2025) studied this question.

synapsesocial.com/papers/68af7c8d7567bf4f94ff3eeahttps://doi.org/10.4103/etmj.etmj-d-25-00005
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