August 25, 2025Food Science & NutritionOpen Access

Curcumin and Resveratrol as Dual Modulators of the STAT3 Pathway in Lung Cancer: A Comprehensive Review

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Comprehensive review highlights curcumin and resveratrol's impact on STAT3 signaling in lung cancer, suggesting potential therapeutic benefits.

Curcumin and resveratrol effectively reduce tumor size by 30%–60% in lung cancer models, and also inhibit critical signaling pathways.
Both compounds suppress STAT3 pathway activation, leading to decreased expression of cancer-related genes and enhanced apoptosis.
Comprehensive review analyzes the role of these natural compounds in overcoming drug resistance in small cell lung cancer.
Impacts of curcumin and resveratrol indicate potential for new cancer therapies, but more studies are necessary for clinical application.

Zamanian et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Comprehensive review highlights curcumin and resveratrol's impact on STAT3 signaling in lung cancer, suggesting potential therapeutic benefits.