A case of early neurological disorder linked to systemic lupus erythematosus with cerebral vasculitis, suggesting a rare presentation of the disease.
We present a case of a 27-year-old female patient with no past medical history of autoimmune disease, consulting for extremities weakness, hallucinations, and arthralgia, which started two weeks before. Decreased limbs strength and hallucinations were evidenced during the physical exam. The patient’s laboratory results showed a systemic inflammatory response with high ANA, low complement levels, and radiological evidence of vasculitis in cerebral arteries of medium and low caliber; as a result, treatment for Systemic Lupus Erythematous was started. Additionally, invasive mechanical ventilation was necessary due to respiratory failure with pleural and pericardial effusion. Finally, treatment produced positive results, as the patient was discharged without any neuro-logical, respiratory or systemic signs and symptoms.
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Cueto et al. (2025) studied this question.