August 25, 2025Discover OncologyOpen Access

Lipid homeostasis dysregulation in oral cancer drives metabolic reprogramming and offers novel diagnostic and therapeutic opportunities

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This review uncovers lipid metabolism dysregulation in oral cancer, highlighting novel diagnostic and therapeutic strategies.

Alterations in lipid homeostasis drive metabolic reprogramming in oral cancer, fostering tumor growth and metastasis.
Patients with oral squamous cell carcinoma show significant changes in serum lipid profiles, suggesting potential biomarkers for diagnosis.
Mechanistic insights reveal key lipid metabolic enzymes influencing OSCC progression, mediated by complex signaling pathways.
Emerging therapeutic strategies targeting lipid metabolism offer new hope for enhancing treatment efficacy in oral cancer patients.

Liang et al. (2025) studied this question.

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