Study on Clinical Data and Molecular Analysis of Admitted Colorectal Cancer Patients in Chittagong Medical College Hospital

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Observational study evaluates colorectal cancer outcomes, revealing genetic mutations and socio-economic factors impacting patients.

Most colorectal cancer patients in the study were middle-aged males from low socio-economic backgrounds, indicating a demographic trend.
Patients presented mainly with rectal and recto-sigmoid junction tumors, with 80% diagnosed as adenocarcinoma, underlining the disease's prevalence.
A significant number of patients (about 53%) had k-ras mutations, highlighting the need for personalized treatment approaches based on genetic makeup.
Molecular analysis supports the genetic basis of colorectal cancer biology, suggesting better-targeted therapeutics based on identified mutations.

Hoque et al. (2025) studied this question.

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