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August 24, 2025Catheterization and Cardiovascular Interventions

MitraClip Versus Surgery for Secondary Mitral Regurgitation: A Systematic Review and Updated Meta‐Analysis

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Authors

JPJuan PinillaUniversidad CESSJSebastian JaramilloAustral UniversityMRMariano Gallo RuelasInstituto de Investigación Nutricional

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Implication

Systematic review compares MitraClip and surgical intervention for secondary mitral regurgitation, suggesting no mortality difference in patients.

Key Points

  • Patients receiving MitraClip showed a lower rate of residual mitral regurgitation ≤ 2+ compared to surgery, demonstrating its effectiveness in reducing MR.
  • The analysis included 11 studies with 1605 patients, revealing a significant difference in MR outcomes with a risk ratio of 0.86 for the MitraClip group.
  • This systematic review utilized data from various databases and assessed differences in clinical outcomes, including mortality and heart failure hospitalizations.
  • Findings suggest that while MitraClip reduces MR, it does not lead to improved survival or functional status compared to surgical options.

Cite This Study

Pinilla et al. (2025) studied this question.

synapsesocial.com/papers/68af79b07567bf4f94ff1cb0https://doi.org/10.1002/ccd.70114
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 14-Year Results of a Randomized Controlled Trial of Percutaneous Repair Versus Surgery for Mitral Regurgitation2013 · 445 citations