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August 24, 2025AntibioticsOpen Access

Escherichia coli Urinary Tract Infections from a Romanian Pediatric Hospital: Antimicrobial Resistance Trends, ESBL Prevalence, and Empirical Treatment Implications

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Authors

DPDaniela PăcurarCarol Davila University of Medicine and PharmacyADAlexandru DinulescuCarol Davila University of Medicine and PharmacyATAndrei-Vlad Totu

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Implication

Retrospective analysis shows high ESBL prevalence in urinary tract infections in children, suggesting tailored empirical treatment strategies.

Key Points

  • ESBL-producing strains were found in 19% of pediatric urinary tract infection cases, complicating treatment options.
  • Infants made up 68.1% of cases, with a notable male predominance in ESBL infections (25% vs. 13.6%).
  • Data was gathered from 248 pediatric patients diagnosed with E. coli urinary tract infections across a Romanian children's hospital.
  • Local antibiogram data offers crucial insights for guiding empirical treatment to combat rising antimicrobial resistance.

Cite This Study

Păcurar et al. (2025) studied this question.

synapsesocial.com/papers/68af79a47567bf4f94ff17e6https://doi.org/10.3390/antibiotics14090855
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