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August 24, 2025International Journal of Molecular SciencesOpen Access

Diabetic Kidney Disease: From Pathophysiology to Regression of Albuminuria and Kidney Damage: Is It Possible?

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Authors

GDGeorgia DoumaniPTPanagiotis TheofilisAVAikaterini Vordoni

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Overview

Review reveals that early intensive treatment for albuminuria improves outcomes in diabetes-linked kidney disease, indicating potential for kidney damage reversal.

Key Points

  • Effective management of diabetic kidney disease improves outcomes and reduces albuminuria levels.
  • Renin-angiotensin-aldosterone system inhibitors and sodium-glucose cotransporter 2 inhibitors show promise in clinical trials.
  • Early combination treatment appears more beneficial compared to traditional monotherapy methods.
  • Management of diabetic nephropathy is complex and requires addressing multiple pathophysiological factors.

Cite This Study

Doumani et al. (2025) studied this question.

synapsesocial.com/papers/68af79a47567bf4f94ff1567https://doi.org/10.3390/ijms26178224
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