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August 22, 2025Rational Pharmacotherapy in CardiologyOpen Access

Mitral regurgitation: etiology, pathogenesis, diagnosis, and outcomes

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Authors

DAD. Yu. AndriyashkinaНДН. А. ДемидоваKGK. R. Gevondyan

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Overview

Observational analysis highlights surgery improves outcomes in patients with mitral regurgitation, suggesting early detection is crucial.

Key Points

  • Surgery improves outcomes in patients with mitral regurgitation, significantly lowering mortality rates for severe cases.
  • Annual mortality rates for surgical treatment are approximately 6% for severe MR in patients over 50 years.
  • Echocardiographic assessments are vital for quantifying MR severity and determining surgical indications.
  • Early detection of mitral regurgitation leads to better surgical outcomes, especially in asymptomatic patients.

Cite This Study

Andriyashkina et al. (2025) studied this question.

synapsesocial.com/papers/68af76b97567bf4f94fefa19https://doi.org/10.20996/1819-6446-2025-3139
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Natural History and Outcomes of Patients With Moderate and Moderate-Severe Mitral Regurgitation2026
  2. 2Clinical outcomes of valve-sparing reconstructive surgery for ischemic mitral regurgitation: a 5-year single-center report and review of current global trends2025
  3. 3The Expanding Therapeutic Armamentarium for Mitral Regurgitation: Surgical and Transcatheter Interventions2026
  4. 4Contemporary Transcatheter Approaches to Mitral Regurgitation.2026 · 1 citations
  5. 5Long-term outcome of patients with heart failure and dynamic functional mitral regurgitation2005 · 285 citations