In-silico Estimation of Flavonoids through Molecular Docking and Assessment of ADMET properties as DPP-IV inhibitor in the treatment of Diabetes Mellitus

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Molecular docking reveals quercetin and kaempferol as DPP-IV inhibitors with favorable ADMET properties for diabetes treatment.

Molecular docking identified quercetin and kaempferol as promising DPP-IV inhibitors for diabetes treatment.
The binding energies for quercetin and kaempferol were -9.3 and -9.2 kcal/mol, respectively, indicating strong interactions.
In-silico analysis included energy minimization and ADMET properties assessment using SWISS ADME software.
Both compounds followed Lipinski's rule of five, suggesting they have good drug-like characteristics.

Anas et al. (2025) studied this question.

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View Full Paper

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Molecular docking reveals quercetin and kaempferol as DPP-IV inhibitors with favorable ADMET properties for diabetes treatment.

Molecular docking identified quercetin and kaempferol as promising DPP-IV inhibitors for diabetes treatment.
The binding energies for quercetin and kaempferol were -9.3 and -9.2 kcal/mol, respectively, indicating strong interactions.
In-silico analysis included energy minimization and ADMET properties assessment using SWISS ADME software.
Both compounds followed Lipinski's rule of five, suggesting they have good drug-like characteristics.

Anas et al. (2025) studied this question.

View Full Paper

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