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August 22, 2025NutrientsOpen Access

Probiotic and Vitamin D Ameliorate TNBS-Induced Colitis by Targeting Mucosal Barrier and Neutrophil Infiltration

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Authors

JLJonathan López-CarrasquilloVRVivianka Y. Ramos-PlazaMCMyrella L. Cruz

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Overview

Administration of probiotic and vitamin D reduced colonic damage in mice, suggesting a novel IBD treatment approach.

Key Points

  • Combined probiotic and vitamin D reduced colonic damage and neutrophil activity in a mouse model of colitis.
  • Mice experienced enhanced mucosal barrier integrity and increased vitamin D levels after treatment with supplements.
  • The approach involved administration of Vivomixx probiotic and vitamin D for 7 days prior to inducing colitis.
  • Findings suggest that using these supplements together may protect against inflammatory bowel disease.

Cite This Study

López-Carrasquillo et al. (2025) studied this question.

synapsesocial.com/papers/68af76a77567bf4f94fef077https://doi.org/10.3390/nu17172719
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