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August 1, 2025Clinical and Applied Thrombosis/HemostasisOpen Access

Oral Anticoagulant Therapy in Patients with Atrial Fibrillation After Intracranial Hemorrhage: A Meta-Analysis of Randomized Controlled Trials

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Authors

GZGuangjing ZhangYWYipeng WuLGLei Gao

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Overview

Meta-analysis shows that oral anticoagulants reduce major vascular events in atrial fibrillation patients post-intracranial hemorrhage, implying increased bleeding risk.

Key Points

  • OACs significantly reduce the occurrence of major vascular events but increase bleeding risk.
  • Participants included three RCTs with a total of 623 individuals assessing OACs post-ICH.
  • Systematic review of randomized controlled trials was employed, focusing on efficacy outcomes related to stroke and vascular events.
  • Decision-making requires evaluating the balance between thromboembolic risks and bleeding risks for individual patients.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68af75277567bf4f94feed78https://doi.org/10.1177/10760296251368889
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