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August 15, 2025LifeOpen Access

Clinical Outcomes of Oral Anticoagulation in Elderly East Asian Patients with Atrial Fibrillation: A Retrospective Single-Center Study

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Authors

KKKyunyeon KimYHYou Mi HwangSCSang-Suk Choi

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Overview

Retrospective study evaluates bleeding and thromboembolic events in elderly patients with AF, suggesting individualized treatment strategies.

Key Points

  • Patients aged ≥80 showed a numerically higher incidence of bleeding, but results were not statistically significant after adjustments.
  • The study involved 502 elderly patients receiving either direct oral anticoagulants or warfarin over eight years.
  • Analysis focused on thromboembolic events, major bleeding, and all-cause mortality among two age groups.
  • Results emphasize the safety and effectiveness of DOACs over age alone in managing anticoagulation therapy.

Cite This Study

Kim et al. (2025) studied this question.

synapsesocial.com/papers/68af75207567bf4f94fee776https://doi.org/10.3390/life15081298
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Age on Bleeding, Stroke, and Mortality in Edoxaban-Treated Patients with Atrial Fibrillation: Results from the ETAF-TR Registry2026
  2. 2Direct oral anticoagulants in older patients with atrial fibrillation and comorbidities: frailty, renal impairment, acute or chronic coronary syndromes, and acute stroke2026 · 1 citations
  3. 3Consider frailty status and comorbidities when choosing anticoagulant treatment for older patients with atrial fibrillation2026
  4. 4Real-World outcomes of oral anticoagulation in patients with atrial fibrillation at high risk of both bleeding anand Asia-Pacificd stroke: observational evidence from three international registries from middle East, Europe2025 · 4 citations
  5. 5Nonvalvular Atrial Fibrillation and Anticoagulation in the Elderly: A Retrospective Cohort Study2026