Complexed Micelles System Based on Ceria Oxide Nanozyme for Bone Remodeling and ROS Scavenging in Periodontitis

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This innovative micelle platform reduces inflammation and promotes tissue regeneration in periodontitis, utilizing cerium oxide and ROS scavenging.

Micelle system alleviates inflammation and promotes regeneration by reducing reactive oxygen species in periodontitis.
Key findings demonstrate that HA-PMs@Ce effectively reprograms macrophages and boosts osteogenic gene expression.
The proposed method includes a self-assembly process to create a multifunctional micelle platform with cerium oxide.
This nanozyme-based approach has potential for treating oral diseases by targeting oxidative stress and inflammation.

Xu et al. (2025) studied this question.

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This innovative micelle platform reduces inflammation and promotes tissue regeneration in periodontitis, utilizing cerium oxide and ROS scavenging.