August 21, 2025International HealthOpen Access

Risk factors and mortality rates for children co-infected with HIV and TB in Ethiopia: a systematic review and meta-analysis

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Discussion

Systematic review identifies high mortality rates in children co-infected with HIV and TB in Ethiopia, suggesting urgent preventive measures.

The pooled mortality rate among HIV and TB co-infected children reached 11.74%, indicating a significant health crisis.
In the analysis of 2025 children, 238 deaths occurred over 1670.6 person-years, underscoring urgent intervention needs.
Meta-regression analyses highlighted critical risk factors related to poor therapy adherence and advanced disease stages.
Addressing anemia and improving healthcare support could reduce mortality in this vulnerable population.

Bizuneh et al. (2025) studied this question.

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Systematic review identifies high mortality rates in children co-infected with HIV and TB in Ethiopia, suggesting urgent preventive measures.