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August 21, 2025Journal of Biochemical and Molecular Toxicology

The Crosstalk Between Protective and Detrimental Interleukin (IL)‐1 Family of Cytokines in Alzheimer's Disease

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Authors

TLTingting LiuXLXiaoyu Li

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Overview

This review examines how interleukin cytokines influence neuroinflammation in Alzheimer's disease, highlighting potential therapeutic strategies.

Key Points

  • Interleukin cytokines may have both protective and detrimental roles in Alzheimer's disease, indicating a complex balance within the immune response.
  • The upregulation of pro-inflammatory cytokines like IL-1α and IL-1β influences neurodegeneration, while anti-inflammatory mediators can provide protection.
  • The review synthesizes current findings on cytokine roles in Alzheimer's disease, emphasizing their potential for therapeutic strategies in managing the condition.
  • Understanding the crosstalk between cytokines and neuroinflammation may open new avenues for effective treatments for Alzheimer's patients.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68af751a7567bf4f94fee4cahttps://doi.org/10.1002/jbt.70460
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