August 22, 2025PeerJOpen Access

Comparative genome analysis of patulin-producing Penicillium paneum OM1 isolated from pears

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The genome of penicillium paneum OM1 reveals 33 secondary metabolite gene clusters, including those for patulin production.
Phylogenetic analysis shows penicillium paneum OM1 shares high genetic identity with other patulin-producing strains, indicating evolutionary links.
Using genome sequencing, 370 carbohydrate-active enzymes were identified in the genome, critical for breaking down plant cell walls.
The study enhances understanding of secondary metabolites, including patulin in penicillium paneum OM1, and informs strategies to reduce fruit contamination.

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Genome sequencing uncovers patulin biosynthetic gene clusters in Penicillium paneum, suggesting new strategies to combat contamination.

Zhao et al. (2025) studied this question.

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